polymerase chain reaction

noun

: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

Examples of polymerase chain reaction in a Sentence

Recent Examples on the Web Officials noted at the time that the method used to find H5N1 in milk—highly sensitive quantitative polymerase chain reaction (qPCR) testing—could not confirm the presence of live virus. Ed Cara / Gizmodo, Quartz, 2 May 2024 Authorities used quantitative polymerase chain reaction (qPCR) testing, which can detect viral DNA particles, but does not identify whether those bits of DNA are capable of replicating or causing disease. Kristen Jordan Shamus, Detroit Free Press, 25 Apr. 2024 See all Example Sentences for polymerase chain reaction 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'polymerase chain reaction.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1985, in the meaning defined above

Time Traveler
The first known use of polymerase chain reaction was in 1985

Dictionary Entries Near polymerase chain reaction

polymerase

polymerase chain reaction

polymeria

Cite this Entry

“Polymerase chain reaction.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/polymerase%20chain%20reaction. Accessed 29 May. 2024.

Medical Definition

polymerase chain reaction

noun
: an in vitro technique for rapidly synthesizing large quantities of a given DNA segment that involves separating the DNA into its two complementary strands, binding a primer to each single strand at the end of the given DNA segment where synthesis will start, using DNA polymerase to synthesize two-stranded DNA from each single strand, and repeating the process
abbreviation PCR

More from Merriam-Webster on polymerase chain reaction

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